The Wall Street Journal fashion writer Christina Binkley doesn't think so anymore, but you have to pay for the comfort. She tried high heeled styles from several brands who claim to be comfortable, Her findings were not exactly earth-shattering: the brand by Taryn Rose, a former podiatrist, is the best. It's also the most expensive. If you are on your feet all day it's totally worth it, - imagine it - wear gorgeous heels all day with no toe pain, no knee or back pain, amazing.
She also ranked Stuart Weitzman, Cole Haan, Naturalizer and Aerosoles shoes, pretty much in that order. I have not had good experiences with Naturalizer shoes, but to each their own.
read the results of her test here.